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Malignant mesenchymoma of the mediastinum initially presenting as benign thymic hyperplasia
Authors:Zeba Attar  Toshihiro Muraji  Yoichi Matsumoto  Eiji Nishijima  Chikara Tsugawa  Hideo Misu  Osamu Mabuchi  Kimio Hashimoto
Affiliation:(1) Aga Khan University Hospital, Pakistan;(2) Department of Surgery, Kobe Children's Hospital, 1-1-1 Takakuradai, 654 Sumaku, Kobe City, Japan;(3) Department of Hematology-Oncology, Kobe Children's Hospital, 1-1-1 Takakuradai, 654 Sumaku, Kobe City, Japan;(4) Department of Pathology, Kobe Children's Hospital, 1-1-1 Takakuradai, 654 Sumaku, Kobe City, Japan
Abstract:
A 17-month-old female was first admitted to our hospital at 7 months of age because of an anterior mediastinal mass associated with mild respiratory symptoms. She underwent a biopsy of the mass that disclosed benign thymic hyperplasia. She came back 8 months later with a larger mass of the mediastinum obstructing the airway. She was intubated and underwent excision of the mass; the histological diagnosis was malignant mesenchymoma. From this experience, it is suggested that more aggressive follow-up, including repeated biopsy, must be considered for a persistent large thymic mass.Offprint requests to: T. Muraji
Keywords:Benign thymic hyperplasia  Mesenchymoma  Mediastinal tumor  Thymus
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