Late bone metastasis from an encapsulated follicular carcinoma of the thyroid withoutcapsular and vascular invasion |
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| Authors: | Yuji Mizukami Akltaka Nonomura Yoshinobu Hayashi Kenji Ohmura Takatoshi Michigishi Masakunl Nogucrtl Shinobu Nakamura Takeshi Ishizaki |
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| Affiliation: | Departments of Pathology Section, Kanazawa University Hospital, Kanazawa;Departments of Surgery, Kanazawa University Hospital, Kanazawa;Departments of Nuclear Medicine, Kanazawa University Hospital, Kanazawa;Departments of Internal Medicine, Kanazawa University Hospital, Kanazawa;Departments of Internal Medicine, Fukui Medical School, Fukui, Japan |
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| Abstract: | ![]()
A unique case of encapsulated follicular carcinoma of the thyroid, which lacked histologic evidence of capsular and vascular Invasion but developed a late bone metastasis, is described. The thyroid tumor was found in a 42-year-old man. It was relatively small (2.5 cm) and totally encapsulated. Histologically, the thyroid tumor showed a microfollicular growth pattern of follicular cells and revealed no histologic evidence of nuclear atypia, mitotic figures or capsular and vascular invasion. The diagnosis of microfollicular adenoma was made and partial thyroidectomy was performed. Bone (rib) metastasis of the thyroid tumor developed 22 years after the thyroidectomy. The present case suggested that capsular and/or vascular invasion is not always sufficient for the diagnosis of encapsulated follicular carcinoma of the thyroid. |
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| Keywords: | bone metastasis encapsulated follicular carcinoma metastasizing adenoma thyroid gland |
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