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岩舒注射液联合NP方案治疗晚期非小细胞肺癌的疗效观察
引用本文:耿丹,马兰,于秋菊. 岩舒注射液联合NP方案治疗晚期非小细胞肺癌的疗效观察[J]. 中华中医药学刊, 2007, 25(6): 1308-1309
作者姓名:耿丹  马兰  于秋菊
作者单位:辽宁省人民医院肿瘤科,辽宁,沈阳,110014
摘    要:目的观察岩舒注射液联合NP方案在晚期非小细胞肺癌(NSCLC)中的疗效。方法:所有病例均经病理和(或)细胞学确诊为晚期NSCLC。其中:治疗组42例行长春瑞滨(NVB)加顺铂(NP)方案化疗同时加用岩舒注射液。对照组26例单用NP化疗,不加用其他生物制剂或中药。结果:治疗组和对照组的总RR分别为28.6%和19.2%(P=0.003),总临床受益率(CBR)分别为71.4%和61.5%(P=0.0032),中位进展时间分别为6.2个月和4.9个月(P=0.06),治疗组与对照组疗后的生活质量(QOL)评分比较有明显提高(P=0.008),毒副反应亦较轻(P=0.006)。结论:岩舒注射液能明显改善晚期非小细胞肺癌(NSCLC)患者的RR、CBR、QOL,并且能增效减毒,具有良好的应用价值。

关 键 词:岩舒注射液  NP方案联合  化疗  非小细胞肺癌  疗效观察
文章编号:1673-7717(2007)06-1308-02
收稿时间:2007-01-06
修稿时间:2007-01-06

Obseve the Therapeutic Efficacy of Yanshu Injection Advanced Non-small Cell Lung Cancer
CENG Dan,MA Lan,YU Qiu-ju. Obseve the Therapeutic Efficacy of Yanshu Injection Advanced Non-small Cell Lung Cancer[J]. Chinese Archives of Traditional Chinese Medicine, 2007, 25(6): 1308-1309
Authors:CENG Dan  MA Lan  YU Qiu-ju
Affiliation:Liaoning Province Hospital, Shenyang 110014, Liaoning, China
Abstract:Objective:To obseve the therapeutic efficacy of Yanshu injection advanced non-small cell lung cancer.Methods:There are two groups,group of Yanshu injection combined with NP,group of NP,68 cases of advanced non-small cell lung cancer.Result: group of Yanshu injection combined with NP had a better effect of raising the quality of life,improve the symptoms than group of NP(P<0.05).Conclusion: group of Yanshu injection combined with NP could improve the symptoms,alleviate the quality of life,reduced the toxicity of chemotherapy.
Keywords:Yanshu injection   NVB plus DDP   non - small cell lung cancer   effective observation
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