锁阳多糖对小鼠胃排空、小肠推进功能的影响

目的:研究锁阳多糖(Cynomorium Songaircum polysalcharides,CSP)对小鼠胃肠运动的影响。方法:采用酚红标记的小鼠胃排空、小肠推进实验,观察CSP对正常小鼠胃排空、小肠推进影响以及对在阿托品负荷的小鼠胃排空、小肠推进抑制的影响。结果:CSP对小鼠的胃排空无显著影响(P>0.05),但对小肠的推进性蠕动作用明显(P<0.05),且成剂量依赖性。结论:CSP对小鼠胃排空的促进作用不明显,CSP对小鼠肠推进具有明显的促进作用,并且可以拮抗由阿托品引起的小鼠肠蠕动的抑制。

Effect of Cynomorium songaricum polysaccharide on mice of gastric emptying and intestinal propulsion

Objective：To study the effect of GSP on gastrointestinal motility in mice. Method：the gastric emptying, intestinal phenolsulfonphthalein propulsion experiments,the effects of CSP on gastric emptying,intestinal propulsion in normal mice and mice gastric emptying,intestinal propulsion in atropine loadinhibition effect. Results：there was no significant effect of CSP on mice gastric emptying （P〉0.05）,but on small intestinal propulsion significantly peristalsis function （P〈0.05）in a dose-dependent;conclusion：CSP had less effect on gastric emptying in mice,CSP has obvious effect on small intestinal propulsion,suppression and can be antagonized by atropine due to the small intestinal peristalsis of mice.