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Phencyclidine blockade of sodium and potassium channels in neuroblastoma cells |
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| Authors: | Y Tourneur G Romey M Lazdunski |
| Abstract: | Voltage-clamp experiments with N1E 115 neuroblastoma cells showed that the phenyclidine (PCP) is an efficient blocker of both the K+ channel (EC50 = 2.6 μM) and the Na+ channel (EC50 = 9.2 μM). Results are also presented for two derivatives of PCP. |
| Keywords: | phencyclidine neuroblastoma cell voltage-champ |
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