B and T Lymphocytes in Blood and Cerebrospinal Fluid in Acute Aseptic Meningitis |
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Authors: | A. FRYDÉ N |
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Affiliation: | Departments of Infectious Diseases and Neurology, University Hospital, Linköping, Sweden |
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Abstract: | B and T cells in blood and cerebrospinal fluid (CSF) were calculated by using the surface membrane immunoglobulin marker for B cells and the capacity to bind sheep erythrocytes to form 'rosettes' as a marker to T cells. Patients with acute aseptic meningitis due to mumps virus or other etiologic agents and with various chronic neurological diseases were investigated. Significantly higher T-cell and lower B-cell values were observed in CSF than in blood in all three groups. No significant differences were found between the three patient groups. An elevation of B cells and a depression of T cells were observed in blood in patients with aseptic meningitis during the course of the disease. |
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