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米力农联合机械通气治疗老年急性心力衰竭的临床效果分析
引用本文:陈桂枝,王益群,应婕. 米力农联合机械通气治疗老年急性心力衰竭的临床效果分析[J]. 中国现代医学杂志, 2021, 0(10): 20-23
作者姓名:陈桂枝  王益群  应婕
作者单位:1.永康市第一人民医院,急诊重症监护室,浙江 金华 321300;2.永康市第一人民医院,心内科,浙江 金华 321300
摘    要:
目的 探讨米力农联合机械通气治疗老年急性心力衰竭患者的临床效果,及其对血清半胱氨酸蛋白酶抑制剂C(CysC)和脑钠肽(BNP)的影响.方法 选取2015年9月—2019年9月永康市第一人民医院收治的老年急性心力衰竭患者62例,采用随机数字表法分为观察组和对照组,每组31例.对照组采用机械通气治疗,观察组在机械通气治疗基...

关 键 词:急性心力衰竭  米力农  机械通气  胱抑素C  B型钠尿肽  老年  临床效果
收稿时间:2020-12-14

Effects of milrinone combined with mechanical ventilation on serum cystatin C and B-type natriuretic peptide in elderly patients with acute heart failure
Gui-zhi Chen,Yi-qun Wang,Jie Ying. Effects of milrinone combined with mechanical ventilation on serum cystatin C and B-type natriuretic peptide in elderly patients with acute heart failure[J]. China Journal of Modern Medicine, 2021, 0(10): 20-23
Authors:Gui-zhi Chen  Yi-qun Wang  Jie Ying
Affiliation:1.Emergency Intensive Care Unit, Yongkang First People''s Hospital, Jinhua, Zhejiang 321300, China; 2. Department of Cardiology, Yongkang First People''s Hospital, Jinhua, Zhejiang 321300, China;2.Emergency Intensive Care Unit, Yongkang First People''s Hospital, Jinhua, Zhejiang 321300, China; 2. Department of Cardiology, Yongkang First People''s Hospital, Jinhua, Zhejiang 321300, China
Abstract:
Objective To investigate the effects of milrinone combined with mechanical ventilation on serum cystatin C (CysC) and B-type natriuretic peptide (BNP) in elderly patients with acute heart failure.Methods Sixty-two elderly patients with acute heart failure in Yongkang First People''s Hospital from September 2015 to September 2019 were divided into observation group (31 cases) and control group (31 cases) according to random number table method. The control group was treated with mechanical ventilation, while the observation group was treated with milrinone on the basis of mechanical ventilation. The course of treatment was 1 week in both groups. Blood gas analysis, cardiac function, serum CysC and BNP levels were compared between the two groups before and after treatment.Results The overall effective rate of the observation group (93.55%) was higher than that of the control group (74.19%) (P < 0.05). The differences of arterial partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2) before and after treatment in the observation group were higher than those in the control group (P < 0.05). The differences of left ventricular end-diastolic dimension (LVDd), left ventricular ejection fraction (LVEF) and stroke volume (SV) before and after treatment in the observation group were higher compared with control group (P < 0.05). Besides, the differences of serum CysC and BNP levels before and after treatment in the observation group were higher than those in the control group (P < 0.05).Conclusions Milrinone combined with mechanical ventilation has an obvious curative effect on elderly patients with acute heart failure, which can significantly decrease the levels of CysC and BNP, improve indicators for blood gas analysis and enhance cardiac function.
Keywords:milrinone  mechanical ventilation  acute heart failure  curative effect  cystatin C  B-type natriuretic peptide  the elderly
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