胰岛素抵抗和脑血管病关系的研究

目的：探讨胰岛素抵抗与脑梗死、脑出血的关系，为针对胰岛素抵抗的治疗可以有效地预防脑血管疾病提供理论依据。方法：选取42例脑梗死（脑梗死组）、40例脑出血（脑出血组）及30例非脑血管病患者（对照组），分别测定空腹胰岛素（FINS）、空腹血糖（FBG），计算胰岛素敏感指数（ISI），各组间进行比较。结果：脑梗死组和脑出血组患者ISI低于对照组（P〈0.05），而FINS高于对照组（P〈0．05），FBG与对照组差异无统计学意义（P〉0．05）。结论：胰岛素抵抗可能是脑血管病的一个重要危险因素。

The Research of the Association between Insulin Resistance and Cerebrovascular Diseases

Objective: To study the relationship between insulin resistance and cerebral infarction or cerebral hemorrhage. Furthermore, effect intervention to decrease insulin resistance would be beneficial to the prevention of stroke. Methods: The level of fasting blood glucose(FBG)and fasting insulin(FINS) were measured respectively in 42 patients with cerebral infarction (CI),40 patients with CH,and 30 patients with other diseases expect for cerebral vascular disease and ISI was tested then compared in each group. Results: FINS was significant higher and ISI was significant lower in the CI group and CH group than that of the control group(P < 0.05). Compared with the control group FBG was not statistically different (P > 0.05). Conclusion: IR is an important risk factor in cerebrovascular diseases.