Effects of immunosuppressors and cytostatics on the extracellular matrix production in experimental nephropathy |
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Authors: | L G Krivoshchapov E M Pal'tseva |
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Institution: | (1) Faculty of Pedagogical Staff Training, I. M. Setchenov Moscow Medical Academy, Moscow, USSR |
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Abstract: | Methylprednisolone increased the content of laminine, cyclosporin increased the content of fibronectin, and cyclophosphamide
suppressed the extracellular matrix production in experimental nephrotoxic nephritis and puromycin aminonucleoside nephrosis.
Therapy should be chosen with due consideration of the extracellular matrix structure in different morphological variants
of chronic glomerulonephritis.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 11, pp. 584–587, November, 1998 |
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Keywords: | extracellular matrix prednisolone cyclophosphamide cyclosporin A |
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