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Disruption of Limbic Pathways in a Case of Profound Amnesia
Authors:A. C. Papanicolaou  K. M. Hasan  C. Boake  Thomas J. Eluvathingal  L. Kramer
Affiliation:1. Department of Pediatrics, Neurology and Neurosurgery , University of Texas-Houston Medical School , Houston, TX, USA Andrew.C.Papanicolaou@uth.tmc.edu;3. Department of Diagnostic and Interventional Imaging , University of Texas-Houston Medical School , Houston, TX, USA;4. Department of Physical Medicine and Rehabilitation , University of Texas-Houston Medical School , Houston, TX, USA
Abstract:
We report a case of episodic amnesia in which the anatomical basis of injury was investigated by diffusion tensor imaging (DTI). Two months after an adult male suffered severe closed head injury, conventional magnetic resonance imaging (CMRI) revealed only a right superior frontal lesion. However, 14 years later, DTI revealed structural anomalies not visible on CMRI involving limbic white matter tracts, notably the fornix, which could explain the amnesia.
Keywords:Diffusion tensor imaging (DTI)  amnesia  fornix  neuroimaging  conventional magnetic resonance imaging (CMRI)
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