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Nekrotisierende Pneumonie mit Staphylococcus aureus (pvl-Gen positiv)
Authors:I. Hörnig-Franz  B. C. Kahl  W. Tebbe  C. Kersting  H. Bürger  K. Nolte  K. Becker  M. Bulla  O. Debus  H. Rabe  E. Harms
Affiliation:1.Allgemeine P?diatrie,Klinik und Poliklinik für Kinder- und Jugendmedizin,Münster;2.Institut für Medizinische Mikrobiologie,Münster;3.Gerhard-Domagk-Institut für Pathologie , Universit?tsklinikum ,Münster;4.Klinik für Kinder- und Jugendmedizin ,Clemenshospital ,Münster;5.Neonatologie und P?diatrische Intensivstation,Klinik und Poliklinik für Kinder- und Jugendmedizin,Münster
Abstract:

Background

Recently, an association between lethal pneumonia in young immunocompetent patients (median age 14.8 years) and the presence of Staphylococcus aureus strains carrying the gene for Panton-Valentine leukocidine (PVL) was described.

Patient

Here we report on a 12-year old girl, who was admitted to the hospital 3 days after the onset of a febrile infection with tachydyspnea. Leukopenia was found haematologically. Radiologically, pleural effusion and pulmonary infiltrates were demonstrated. The progression of the disease was rapid, leading to cerebral death within 10 days of diagnosis.

Results

A PVL-positive S. aureus strain was cultured from relevant samples both pre and post mortem.
Keywords:
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