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Personality correlates of platelet monoamine oxidase activity and red cell lithium transport
Authors:Rita Shaughnessy  Elizabeth Dorus  Ghanshyam N. Pandey  John M. Davis
Affiliation:1. Rita Shaughnessy, Ph.D., is Research Associate, and Elizabeth Dorus, Ph.D., is Research Associate-Assistant Professor, Department of Psychiatry, University of Chicago, USA;2. Ghanshyam N. Pandey, Ph.D., is Director of Biological Research Laboratory, and John M. Davis, M.D., is Director of Research Department, Illinois State Psychiatric Institute, USA
Abstract:
Platelet monoamine oxidase (MAO) activity and the ratio of red cell to plasma lithium concentrations (Li ratio) may be important in the pathophysiology of, and genetic vulnerability to, some psychiatric disorders. By using the Clinical Analysis Questionnaire, we assessed personality correlates of MAO activity and the Li ratio in vitro in a sample of psychiatrically normal adult women. We found that there were correlates of each variable, and a unique constellation of personality traits when the two variables were considered simultaneously.
Keywords:Platelet monoamine oxidase  red-cell-lithium transport  personality correlates of biochemical variables  Clinical Analysis Questionnaire
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