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Herpetic Panophthalmitis: A Diagnostic Dilemma
Authors:L. M. Hassman  M. M. Chung  M. Gonzalez
Affiliation:1. Ophthalmology, Washington University in Saint Louis, Saint Louis, Missouri, USA;2. Ophthalmology, University of Rochester David and Ilene Flaum Eye Institute, Rochester, New York, USA
Abstract:
ABSTRACT

Purpose: To describe an uncommon presentation of ocular infection caused by human herpes simplex virus 2 (HSV-2).

Methods: Case report.

Results: A 32-year-old female with no prior history of mucocutaneous herpesvirus infection presented with a minimally painful hypertensive granulomatous panophthalmitis and optic neuropathy that was initially suspected to be orbital cellulitis. Her disease progressed despite antibiotic and steroid treatment, and HSV-2 was ultimately identified in the vitreous.

Conclusion: Although rare, ocular infection by human herpesvirus can present as a panophthalmitis. The case is discussed in the context of two previously reported cases of herpes simplex panophthalmitis, as well panophthalmitis caused by varicella zoster virus.
Keywords:HSV-2  Panophthalmitis  Acute retinal necrosis
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