Quality of oral anticoagulation control in Chinese patients with non-valvular atrial fibrillation: a prospective controlled study |
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| Authors: | Yaqian Li Jingjing Yu Yun Kuang Chengkun Wu Liu Yang Qiulian Fang |
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| Institution: | 1. Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China;2. Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, China;3. Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China;4. State Key Laboratory of High Performance Computing, College of Computer, National University of Defense Technology, Changsha, China;5. School of Mathematics and Statistics, Central South University, Changsha, China |
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| Abstract: | Abstract Objective The sex, age, medical history, treatment, tobacco use, race risk (SAMe-TT2R2) Score; the sex, age, medical history, treatment, tobacco use, genotype combination (SAMe-TT2G2) Score; and the so-called modified SAMe-TT2R2 scores have been proposed to predict the anticoagulation quality for patients with non-valvular atrial fibrillation (NVAF). The data from a prospective controlled study is used to validate the SAMe-TT2R2 and SAMe-TT2G2 scores in Chinese NVAF patients treated with warfarin and to evaluate the association of factors with time in therapeutic range (TTR) to predict the quality of oral anticoagulation control. |
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| Keywords: | Atrial fibrillation warfarin oral anticoagulation TTR |
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