|
|||||
|
|
Failure of chronic antidepressant treatment to alter growth hormone response to clonidine |
|
| Authors: | Dennis S. Charney George R. Heninger David E. Sternberg |
| Affiliation: | 1. Dennis S. Charney, M.D.,is Assistant Professor, Department of Psychiatry, Yale University School of Medicine Connecticut Mental Health Center, 34 Park St., New Haven, CT 06519, U.S.A.;2. George R. Henninger, M.D.,is Professor, Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, 34 Park St., New Haven, CT 06519, U.S.A.;3. David E. Sternberg, M.D., is Assistant Professor, Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, 34 Park St., New Haven, CT 06519, U.S.A. |
| Abstract: | The effect of 4 to 6 weeks of treatment with the antidepressants, desmethylimipramine and amitriptyline, on the growth hormone response to clinidine was studied in 12 depressed patients. In contrast to the reported effects of clonidine in healthy subjects, clonidine did not significantly increase growth hormone secretion in the depressed patients before treatment. The antidepressant treatments did not alter the growth hormone response to clonidine in either treatment responders or nonresponders. |
| Keywords: | Depression antidepressant treatment clonidine growth hormone |
| 本文献已被 ScienceDirect 等数据库收录！ | |