| 西洋参茎叶皂甙对大鼠实验性肝损伤的影响 |
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| 引用本文： | 赵玉珍,刘蕾,陈立平,谭宏,王淑湘. 西洋参茎叶皂甙对大鼠实验性肝损伤的影响[J]. 中成药, 2000, 22(3): 219-220 |
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| 作者姓名： | 赵玉珍 刘蕾 陈立平 谭宏 王淑湘 |
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| 作者单位： | 1. 佳木斯大学基础医学院,黑龙江,佳木斯,154002
2. 佳木斯中心医院,黑龙江,佳木斯,154002 |
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| 摘 要： | 目的：观察国产西洋参茎叶皂甙（ＰＱＳ）对员伤的保护作用。方法：采用急性乙醇中毒大鼠模型为研究对象。结果：ＰＱＳ能降低血清过氧化脂质（ＭＤＡ）、血清谷丙转氨酶（ＳＧＰＴ）、血清谷草转氨酶（ＳＧＯＴ）活性，减少肝脏ＭＤＡ的生成，增加肝谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）活性。结论：提示ＰＱＳ对员伤具有保护作用。
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| 关 键 词： | 西洋参茎叶皂甙 大鼠 肝损伤 |
| 文章编号： | 1001-1528(2000)03-0219-02 |
| 修稿时间： | 1999-01-30 |
Effect of Saponins of Stems and Leaves of Radix Panacis Quinquefolii on Experimental liver Injury of Rats |
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| ZHAO Yu-zhen,LIU Lei,CHEN Li-ping,TAN Hong,WANG Shu-xiang. Effect of Saponins of Stems and Leaves of Radix Panacis Quinquefolii on Experimental liver Injury of Rats[J]. Chinese Traditional Patent Medicine, 2000, 22(3): 219-220 |
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| Authors: | ZHAO Yu-zhen LIU Lei CHEN Li-ping TAN Hong WANG Shu-xiang |
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| Abstract: | Objective:To observe the protective action of saponins of stem and Leaf of Radix Panacis Quinguefolii on liver injury in rats. Methods:In this study, the acute ethylism rat model was used. Results:The saponins of stem and leaf of Radix Panacis Quinguefolii could inhibit the activities of MDA, SGPT, SGOT; decrease the formation of MAD in liver; increase the activity of GSH Px. Conclusion: The saponins of stem and leaf of Radix Panacis Quinquefolii have prostective action on liver injury. |
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| Keywords: | saponins of stem and leaf of Radix Panacis Quinquefolii acute ethylism rat model liver injury |
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