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乙肝病毒标志物定量检测与肝脏损害的相关性研究
引用本文:张永红 田沂 蒋永芳 梁骏. 乙肝病毒标志物定量检测与肝脏损害的相关性研究[J]. 实用临床医学(江西), 2005, 6(12): 4-5
作者姓名:张永红 田沂 蒋永芳 梁骏
作者单位:中南大学湘雅二医院肝病研究中心,湖南长沙410011
摘    要:目的:探讨乙肝病毒标志物定量检测与肝脏损害的关系。方法:采用人院时第一份血清,应用时间分辨免疫荧光分析法(TRIFA)测定696例乙肝患者病毒标志物的含量,同步监测肝功能。结果:HBeAb与ALT呈负相关(r=-0.346,P〈0.05),HBeAg与TBIL呈负相关(r=-0.230,P〈0.05),而乙肝病毒标志物定量与AST、PAB、ALB、PT无关。结论:不能完全以乙肝病毒标志物的定量来判断患者肝功能的好坏。

关 键 词:肝炎病毒 乙型 标志物 肝功能 相关性分析
文章编号:1009-8194(2005)12-0004-02
收稿时间:2005-08-01
修稿时间:2005-08-01

Correlation between the Quantities of the Hepatitis B Virus Markers and Hepatic Injury
Zhang Yong-hong, Tian Yi, Jiang Yong-fang, Liang Jun. Correlation between the Quantities of the Hepatitis B Virus Markers and Hepatic Injury[J]. Practical Clinical Medicine, 2005, 6(12): 4-5
Authors:Zhang Yong-hong   Tian Yi   Jiang Yong-fang   Liang Jun
Abstract:Objective: To investigate the relationship between the quantities of the hepatitis B virus markers and hepatic injury.Methods:Six hundred and ninety six inpatients suffering from viral hepatitis type B were selected.The quantities of the hepatitis B virus markers were detected by time-resolved immunofluorometric assay at entrance,so did liver functions.Results:There were negative correlations between HBeAb and ALT(r=-0.346,P<0.05)as well as between HBeAg and TBIL(r=-0.230,P<0.05).There was no significant correlation between the quantities of the hepatitis B virus markers and either of AST,PAB,ALB,or PT.Conclusion:We could not judge the liver function by the quantities of the hepatitis B virus markers.
Keywords:hepatitis B virus   markers   liver functions   correlation analysis
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