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| 河北省1997～2002年急性弛缓性麻痹病例非脊髓灰质炎肠道病毒监测分析 | |
| 引用本文： | 宋慧军 张振国 张晓晔 陈玫 郭彧. 河北省1997～2002年急性弛缓性麻痹病例非脊髓灰质炎肠道病毒监测分析[J]. 中国疫苗和免疫, 2004, 10(6): 340-342 |
| 作者姓名： | 宋慧军 张振国 张晓晔 陈玫 郭彧 |
| 作者单位： | 河北省疾病预防控制中心 石家庄050021(宋慧军，张振国，张晓晔，陈玫)，河北省疾病预防控制中心 石家庄050021(郭彧) |
| 摘 要： | 河北省 1 997～ 2 0 0 2年急性弛缓性麻痹 (AFP)病例病毒学监测中 ,共有 2 0 2例分离到非脊髓灰质炎肠道病毒(NPEV) ,年均NPEV分离率 1 0 1 %。对分离到的NPEV毒株进行了型别鉴定 ,在明确定型的 1 0 3株NPEV中 ,包括柯萨奇病毒 (Coxsackievirus ,Cox )A组 1个型 ;Cox B组 5个型 ;埃可病毒 (ECHO) 1 4个型。RD细胞对ECHO和Cox A9敏感 ,HEp 2细胞对Cox B敏感。取消HEp 2细胞的使用 ,会造成多数Cox B和一些未能定型的NPEV漏检 ,使NPEV分离率明显降低。NPEV感染有明显的夏秋季高峰 ,主要集中在小年龄组儿童 ,以 1岁和 2岁为多。 |
| 关 键 词： | 急性弛缓性麻痹 非脊髓灰质炎肠道病毒 监测 |
| 文章编号： | 1006-916X(2004)06-0340-03 |
| 修稿时间： | 2004-05-12 |
Analysis of Non-Polio Enterovirus Surveillance of Acute Flaccid Paralysis Cases in Hebei Province During 1997-2002 |
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| SONG Hui-jun,ZHANG Zhen-guo,ZHANG Xiao-ye,et al.. Analysis of Non-Polio Enterovirus Surveillance of Acute Flaccid Paralysis Cases in Hebei Province During 1997-2002[J]. Chinese Journal of Vaccines and Immunization, 2004, 10(6): 340-342 | |
| Authors: | SONG Hui-jun ZHANG Zhen-guo ZHANG Xiao-ye et al. |
| Abstract: | In Hebei Province during 1997-2002,the non-polio enterovirus (NPEV)was isolated from 202 Acute Flaccid paralysis(AFP)cases,the average NPEV isolation rate was 10.1% per year. All isolated NPEVs were conducted type identification,103 strains of NPEV were identified definitely which included 1 type of Coxsackie virus (Cox.)A, 5 types of Cox.B, and 14 types of ECHO virus.RD cells were sensitive to ECHO and Cox.A9 viruses while HEp-2 cells were sensitive to Cox.B viruses.Most of Cox.B viruses and some unknown NPEV might be missed if HEp-2 cell was not used, so the NPEV isolation rate would be decreased obviously.The NPEV infection peaks were in summer and fall, and mainly among younger children, especially the children aged 1 and 2 years old. |
| Keywords: | Acute flaccid paralysis Non-polio enteroviruses Surveillance |
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