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A case of anaphylactoid purpura associated with nephrosis followed by pulmonary tuberculosis
Authors:Zen Isobe  Tatsuo Suga  Yasuhiro Aoki  Fumiaki Aoki  Kana Ikeda  Manabu Ueno  Toshitaka Maeno  Masahiko Kurabayashi
Affiliation:Department of Respiratory Medicine, Gunma University School of Medicine.
Abstract:
A 54-year old man was admitted to our hospital because of high fever, productive cough and purpura in both legs in June 2005. Urinalysis showed microscopic hematuria and proteinuria. Chest radiograph showed consolidation of right upper field. Because acid-fast bacilli and polymerase chain reaction test for Mycobacterium tuberculosis were positive in bronchial lavage fluid, we made a diagnosis of pulmonary tuberculosis, and prescribed antituberculosis therapy with isoniazid, rifampicin, ethambutol and pyrazinamide. In addition, anaphylactoid purpura was diagnosed by skin biopsy. In July 2005, renal function was deteriorated and nephrosis appeared. We treated with corticosteroid in addition to antituberculosis therapy. His symptoms and renal dysfunction improved. We report a rare case of an anaphylactoid purpura following occurence of pulmonary tuberculosis.
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