| 磁共振引导高强度聚焦超声治疗子宫肌瘤临床研究 |
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| 引用本文： | 陈军臣 许永华 王智彪等. 磁共振引导高强度聚焦超声治疗子宫肌瘤临床研究[J]. 中华临床医师杂志(电子版), 2014, 0(8): 1512-1520 |
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| 作者姓名： | 陈军臣 许永华 王智彪等 |
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| 作者单位： | [1]重庆医科大学生物医学工程学院,400016; [2]中国科学院上海临床中心上海徐汇中心医院医学影像科,400016; |
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| 基金项目： | 科技部“十二五”支撑计划课题（2011BAI14B1） |
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| 摘 要： | 磁共振引导高强度聚焦超声(MRgHIFU)利用MRI准确解剖定位引导及实时温度监测功能和高强度聚焦超声波,从体外将超声能量聚集于治疗靶区使其温度瞬间升高,选择性灭活体内某特定区域病灶,而对病灶周围及声通道上的组织结构无损害或损害很少。本文对MRgHIFU治疗子宫肌瘤的作用机制、温度监控技术、临床治疗适应证和禁忌证、治疗疗效和并发症及其优势和不足进行综述。
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| 关 键 词： | 磁共振成像 平滑肌瘤 聚焦超声 |
Clinical research of treatment of uterine fibroids by MR-guided high intensity focused ;ultrasound |
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| Affiliation: | Chen Junchen, Xu Yonghua, Wang Zhibiao, Chen Wenzhi (School of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, China) |
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| Abstract: | Magnetic resonance guided high intensity focused ultrasound （MRgHIFU） employs MRI’s function such as accurate anatomical guidance and real-time temperature mapping for monitoring HIFU to accumulate ultrasound energy at the focal region, which would result in the temperature elevate in the targeted tissues for ablation without injures of the structures around the focus and at acoustic path. In this paper, the mechanism of MRgHIFU treatment of uterine fibroids, temperature mapping technology, clinical indications and contraindications, therapeutic efficacy and complications, and the advantages and disadvantages were reviewed. |
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| Keywords: | Magnetic resonance imaging Leiomyoma Focused ultrasound |
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