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| 老年肺癌组织学类型、分化及其P53蛋白表达 | |
| 引用本文： | 纪正春,刘平,孙立新,宋志杰,宋立刚,赵晓明,胡建功,金小平. 老年肺癌组织学类型、分化及其P53蛋白表达[J]. 中国老年学杂志, 2000, 20(3): 147-148 |
| 作者姓名： | 纪正春 刘平 孙立新 宋志杰 宋立刚 赵晓明 胡建功 金小平 |
| 作者单位： | 1. 承德医学院附属肛肠医院,承德,067000 2. 承德医学院附属医院 |
| 摘 要： | 目的 研究老年肺癌组织学特点及其Ｐ５３蛋白的表达。方法 肺癌组织学类型按ＷＨＯ标准进行分类，Ｐ５３蛋白的表达采用免疫组化技术。结果 老年组肺癌的组织学类型与非老年组不同，差异有显著性（Ｐ〈０．０５）；Ｐ５３蛋白总阳性率为４２．８６％，两者间差异没有显著性（Ｐ〉０．０５）。结论 老年肺癌的组织学类型有其自己的特点，Ｐ５３基因在肺癌的发生发展中具有重要意义。 |
| 关 键 词： | 肺肿瘤 免疫组织化学 P53蛋白 老年人 分化 |
| 修稿时间： | 1999-04-11 |
The Histological classification(Typing) of the elderly lung cancer patients,its differentiation and P53 protein expression |
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| Ji Zhengchun,Sun Lixin,Liu Ping et al. The Histological classification(Typing) of the elderly lung cancer patients,its differentiation and P53 protein expression[J]. Chinese Journal of Gerontology, 2000, 20(3): 147-148 | |
| Authors: | Ji Zhengchun Sun Lixin Liu Ping et al |
| Abstract: | To study the histological features of elderly lung cancer patients and it's expression of P53 protein. Methods The histological types were determined according to WHO standard and the immunohistochemical stain was used on the expression of P53 protein. Results There were differences of the histological types between the aged and non-aged patients. The total positive rate of P53 was 42. 86 % with no statistical differences between these two groups. Conclusions the histological types of lung cancer in aged patients have their own features and P53 gene plays an important role in the progression of lung cancer. |
| Keywords: | Aged Lung neoplasms Immunohistochemistry P53 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |