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The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging
Affiliation:1. Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA;2. Department of Comparative Medicine, Yale School of Medicine, New Haven, CT 06520, USA;3. Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA;4. Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA;5. Section of Immunology, Washington School of Medicine, St Louis, MO 63110, USA;6. Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA;7. Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT 06520, USA
Abstract:
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  • Keywords:SPARC  matricellular protein  caloric restriction  macrophage  inflammation  TLR4  interferon-stimulated gene
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