网状铜丝留置联合平阳霉素注射治疗复杂性海绵状静脉畸形

Objective To evaluate the therapeutic effect of retained copper wires combined with pingyangmycin(PYM) injection for complicated cavernous venous malformation. Methods The location of venous malformation was detected by physical examination and MRI. The copper wires in 0.2 mm width were used to puncture the lesion repeatedly and retained in the lesion to form a net. After that, 8 mg PYM was injected into the residue malformed veins. 8～10 days later, the copper wires were taken out and necrotic tissue was squeezed out. The wounds of punctual holes healed through dressing. The patients received postoperative MRI to evaluate the therapeutic effect. Results From Jan. 2002 to Dec. 2008, 45 cases were treated. The patients were followed up for 1～3 years. 51.1% (23/45) of the lesions shrinked markedly or even disappeared. 42.2% (19/45) of the lesions reduced. 6.67% (3/45) of the lesions didn't change. There was no complication like invasive infection. Conclusions It is very effective to treat complicated cavernons venous malformation with retained copper wires combined with pingyangmycin injection.

Treatment of complicated cavernous venous malformation with retained copper wires combined with pingyangmycin injection