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某院近2年革兰阴性杆菌耐药性监测及临床意义
引用本文:江镜全,郭旭光,陈琼,夏勇. 某院近2年革兰阴性杆菌耐药性监测及临床意义[J]. 检验医学与临床, 2013, 0(11): 1350-1351,1353
作者姓名:江镜全  郭旭光  陈琼  夏勇
作者单位:广州医学院第三附属医院检验科,广东广州510150
基金项目:广东省广州市医药卫生科技一般引导项目(项目编号:20121A011160)
摘    要:目的分析本院2010、2011年临床分离革兰阴性杆菌耐药性,为临床合理用药提供依据。方法采用K-B法进行革兰阴性杆菌药敏试验检测,采用WHONET5.4软件进行数据统计分析。结果 2011年分离革兰阴性菌1 325株,其中大肠埃希菌318株、铜绿假单胞菌266株、鲍曼不动杆菌237株、肺炎克雷伯菌217株,对抗菌药物的敏感率较2010年有所下降。结论革兰阴性杆菌对多种抗菌药物的耐药性明显上升,应加强病原菌耐药性监测,为临床合理用药提供依据。

关 键 词:革兰阴性杆菌  大肠埃希菌  鲍曼不动杆菌  铜绿假单胞菌

Antimicrobial resistance of Gram-negative bacilli isolated from a hospital and its clinical significance
JIANG Jing-quan,GUO Xu-guang,CHEN Qiong,XIA Yong. Antimicrobial resistance of Gram-negative bacilli isolated from a hospital and its clinical significance[J]. Laboratory Medicine and Clinic, 2013, 0(11): 1350-1351,1353
Authors:JIANG Jing-quan  GUO Xu-guang  CHEN Qiong  XIA Yong
Affiliation:(Department of Clinical Laboratory Medicine,Third Hospital Affiliated to Guangzhou Medical College,Guangzhou,Guangdong 510150,China)
Abstract:Objective To analyze the drug resistance of Gram-negative bacilli isolated from our hospital in 2010 and 2011 and provide scientific evidence for reasonable usage of antibiotics.Methods Drug sensitivity test was performed by using K-B method and all data were analyzed by using WHONET5.4 software.Results Among 1 325 strains of Gram-negative bacilli,the top four of the isolating rate were Escherichia coli(n=318),Pseudomonas aeruginosa(n=266),Acinetobacter baumannii(n=237) and Klebsiellar pneumonia(n=217),with lower drug sensitivity compared with 2010.Conclusion Drug resistance status of Gram-negative bacilli could be very serious.More attention should be paid to the detection of pathogens and drug resistance in hospital to prevent the outbreak.
Keywords:Gram-negative bacilli  Escherichia coli  Acinetobacter baumannii  Pseudomonas aeruginosa
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