| 高渗氯化钠溶液对水钠调节激素的影响 |
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| 引用本文： | 吴新文 刘怀琼. 高渗氯化钠溶液对水钠调节激素的影响[J]. 中华麻醉学杂志, 1995, 15(1): 28-30 |
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| 作者姓名： | 吴新文 刘怀琼 |
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| 作者单位： | 解放军第四一二一医院!广州市510318(吴新文，王忠懋)，第三军医大学大坪医院麻醉科!重庆市(刘怀琼) |
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| 摘 要： | 比较３０例硬膜外阻滞择期手术患者，输入７．５％ＨＳ和５％ＧＳ后血浆ＡＤＨ、ＰＲＡ、ＡⅡ及ＡＬＤ变化。输入 ＨＳ后 １０分钟 ＡＤＨ增加 ３３％，ＡⅡ、ＡＬＤ分别下降 ３７． ４％和 １６． ５％，６０分钟时 ＡＤＨ仍维持在高水平，ＡⅡ、ＡＬＤ亦未完全恢复。输入ＧＳ后 ＡＤＨ有增加趋势，但无统计学意义，Ａ Ⅱ于 １０分钟时轻度降低，６０分钟恢复，ＡＬＤ逐渐增加，６０分钟最明显（增加 ４６． ２％）。提示 ＨＳ可刺激 ＡＤＨ释放，抑制ＲＡＡＳ活性，激素的变化对ＨＳ改善肾功能可能具有重要介导作用。
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| 关 键 词： | 高渗氯化钠溶液 水钠调节激素 |
Effects of hypertonic saline solution on regulatory hormone of water and sodium |
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| Wu Xinwen,Wang Zhongmao,Liu Huaiqiong.. Effects of hypertonic saline solution on regulatory hormone of water and sodium[J]. Chinese Journal of Anesthesilolgy, 1995, 15(1): 28-30 |
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| Authors: | Wu Xinwen Wang Zhongmao Liu Huaiqiong. |
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| Abstract: | The effects of hypertonic saline solution (HS) on antidiuretic hormone (ADH), plasma renin activity (PRA),anglotensin II (AII),and aldosterone (ALD) were evaluated, 30 patients scheduled for elective operations were infused with 7. 5 AHS (n = 20 ) or 5 % dextrose (n = 10) 4 ml/kg 20 min before epidural anesthesia. In HS group,the ADH increased about 33%,All and ALD decreased 37. 4%, 16. 5% respectively. In dextrose group, ADH increased but statistically not significant , All decreased transiently and ALD increased about 46. 2%. It is suggested that HS may stimulate the secretion of ADH and depress the activity of RAAS. These hormonal changes may play an important role for improving the renal function. |
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| Keywords: | Hypertonic saline solution Regulatory hormone of water and sodium |
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