| 应用MATLAB求算静脉注射给药的药动学参数 |
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| 引用本文： | 杨帆. 应用MATLAB求算静脉注射给药的药动学参数[J]. 抗感染药学, 2009, 6(3): 157-161 |
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| 作者姓名： | 杨帆 |
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| 作者单位： | 华南农业大学兽医学院,广东,广州,510642 |
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| 摘 要： | 目的:应用MATLAB求算静脉注射给药的药动学参数。方法:利用MATLAB的inline和nlinfit命令进行非线性拟合,求解药动学参数。结果:MATLAB可方便快速求解静脉注射给药途径下的各个药动学参数,结果与3P97计算结果相当。结论:本方法操作简便、界面直观、结果可靠、易于推广,可用于临床教学或实验中药动学参数的计算。
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| 关 键 词： | 非线性回归 拟合 MATLAB 静脉注射 药动学参数 |
Calculation of Pharmacokinetic Parameters by Intravenous Injection Based on MATLAB |
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| YANG Fan. Calculation of Pharmacokinetic Parameters by Intravenous Injection Based on MATLAB[J]. Anti-infection Pharmacy, 2009, 6(3): 157-161 |
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| Authors: | YANG Fan |
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| Affiliation: | YANG Fan( School of Veterinary Medicine, South China Agricultural University, Guangzhou Guangdong 510642, China) |
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| Abstract: | Objective： To calculate pharmacokinetic parameters by intravenous injection based on MATLAB. Methods：To calculate pharmacokinetic parameters mainly using the commands of ＂inline＂ and ＂linfit＂ . Results： MATLAB can be used to directly calculate the pharmacokinetic parameters, with calculation results in line with those calculated based on 3P97. Conclusion： The established method is simple, direct-viewing, reliable and easy to be operated and popularized, and it can be used to calculate pharmacokinetic parameters in clinical teaching or experiments. |
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| Keywords: | MATLAB |
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