应用A型肉毒素治疗眼睑痉挛

目的：讨论应用A型肉毒素治疗眼睑痉挛的疗法。方法：对30例眼睑痉挛患者用BTXA进行局部眼睑下注射前均行眼部常规检查和确定痉挛强度，按治疗标准进行评估。结果：3天后症状完全缓解20例(66．67％)，6例明显缓解(20％)，4例部分缓解(13．33％)，10天后3例患者治疗效果不理想，再次重复注射，完全缓解，效果达100％。所有患者治疗期间未出现并发症。结论：BTXA局部注射是治疗眼睑痉挛的一种安全、有效、简便的方法，可以推广。

Treatment of blepharospasm with type A botulinum toxin

Objective To investigate the effect of botulinum in the treatment of blepharospasm. Methods After having rutine examination we took subcutaneous injection of botulinum toxin type A to 30 cases with blepharospasm,then evaluated the results of them. Results After 3 days of the injection there were 20 out of 30 cases(66.67%),whose symptoms were totally disappear,6 cases(20%) obviously got better and 4 cases(13.33%)partly got better.10 days later,there were 3 cases(10%) whose effects were good enough and had been taken the second injection of botulinum,which resulted in satisfied effect in the end.All cases hadn't complained any complications or adverse reactions. Conclusion The subcutaneous injection of botulinum toxin type A was a safe,effective and simple measure in treatment of blepharospasm and can extend in the clinical work.