胰腺癌综合治疗的研究进展

胰腺癌发病隐匿,进展迅速,预后极差,病死率高。手术是主要治疗手段,但因早期诊断困难,大部分患者确诊时已无手术机会。随着新型化疗药物和方案的不断涌现;放疗技术及设备的明显改进和以基因治疗和免疫治疗为代表的生物疗法的发展,胰腺癌的治疗手段更加多样化和正规化。正确运用综合治疗有望改善胰腺癌的预后。

Multimodality approaches for pancreatic cancer

Pancreatic cancer is a devastating illness that has the short survival. The poor survival associated with pancreatic cancer stems from the advanced stage at diagnosis for the majority of cases. In many instances, even in patients with apparently localized resectable tumors, distant micrometastases already exist. So although surgery remains at the center of any potentially curable case, the need for other treatment modalities is paramount to maximize survival. With the advances in chemotherapy, improvements in radiation technology and developments of biologic therapy, the role of combined-modality therapy for pancreatic cancer has become more and more important. This article try to summarize the current state of the management and future directions regarding the multimodality approach to pancreatic cancer.