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鼻咽癌136例调强放疗后预后因素分析
引用本文:陈诚,黄生富,何侠. 鼻咽癌136例调强放疗后预后因素分析[J]. 肿瘤学杂志, 2011, 17(12): 907-910
作者姓名:陈诚  黄生富  何侠
作者单位:江苏省肿瘤医院,江苏南京,210009
基金项目:江苏省自然科学基金,江苏省肿瘤医院科研基金
摘    要:
[目的]分析鼻咽癌患者调强放疗后的预后因素。[方法]2005年3月至2009年5月136例经病理证实鼻咽低分化鳞状细胞癌患者入组,所有病例行调强放疗治疗后定期随访,中位随访期38个月(5~74个月)。[结果]Kaplan-Meier分析显示性别对无瘤生存率有显著性影响(P=0.039),T分期、N分期、临床分期对无转移生存率(P值分别为0.017、0.006、0.012)和无瘤生存率(P值分别为0.007、0.017、0.011)有显著性影响。Cox回归模型分析显示临床分期是无转移生存率(RR=2.963,P=0.002)和无瘤生存率(RR=2.520,P=0.002)的独立预后因素。[结论]临床分期为鼻咽癌的独立预后因素,2008分期系统能够很好地预测鼻咽癌的生存状况。

关 键 词:鼻咽肿瘤  调强放疗  预后  2008分期

Prognostic Factors of 136 Cases with Nasopharyngeal Carcinoma with Intensity Modulated Radiation Therapy
CHEN Cheng,HUANG Sheng-fu,HE Xia. Prognostic Factors of 136 Cases with Nasopharyngeal Carcinoma with Intensity Modulated Radiation Therapy[J]. Journal of Chinese Oncology, 2011, 17(12): 907-910
Authors:CHEN Cheng  HUANG Sheng-fu  HE Xia
Affiliation:CHEN Cheng,HUANG Sheng-fu,HE Xia(Jiangsu Cancer Hospital,Nanjing 210009,China)
Abstract:
[Purpose] To evaluate prognostic factors in patients with nasopharyngeal carcinoma(NPC) undergoing intensity modulation radiated therapy(IMRT).[Methods] From March 2005 to December 2008,136 patients with nasopharyngeal poorly differentiated squamous-cell carcinoma pathologically proven were enrolled.All patients received IMRT,and followed up with median follow-up of 38 months(5~74 months).[Results] Kaplan-Meier analysis showed that gender was significantly correlated with disease-free survival rate(DFS)(P=0...
Keywords:nasopharyngeal neoplasms  intensity modulation radiation therapy  prognosis  Chinese 2008 staging system  
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