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Sympathetic Input to Multiple Cell Types in Mouse and Human Colon Produces Region-Specific Responses
Authors:Kristen M. Smith-Edwards  Brian S. Edwards  Christina M. Wright  Sabine Schneider  Kimberly A. Meerschaert  Lindsay L. Ejoh  Sarah A. Najjar  Marthe J. Howard  Kathryn M. Albers  Robert O. Heuckeroth  Brian M. Davis
Affiliation:1. Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;2. Pittsburgh Center for Pain Research, University of Pittsburgh, Pittsburgh, Pennsylvania;3. Center for Neuroscience at the University of Pittsburgh, Pittsburgh, Pennsylvania;4. The Children’s Hospital of Philadelphia Research Institute, Philadelphia, Pennsylvania;5. Department of Neurosciences, University of Toledo, Toledo, Ohio;1. Department of Gastroenterology;2. Department of Microbiology, Medanta Super Speciality Hospital Lucknow, Uttar Pradesh, India;1. Department of Gastroenterology;2. Department of Diagnostic Imaging, Sheba Medical Center affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Israel
Abstract:
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  • Keywords:Gastrointestinal  Interstitial Cells of Cajal  Platelet-Derived Growth Factor Receptor–α  GCaMP  ACSF"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0035"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  artificial cerebrospinal fluid  CG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0045"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  celiac ganglion  CMMC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0055"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  colonic migrating motor complex  GFP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0065"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  green fluorescent protein  HGN"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0075"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  hypogastric nerve  IC-MY"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0085"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  interstitial cells in myenteric plexus  ICC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0095"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  interstitial cells of Cajal  IMG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0105"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  inferior mesenteric ganglion  LCN"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0115"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  lumbar colonic nerve  MN"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0125"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  mesenteric nerve  NPY"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0135"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  neuropeptide Y  PBS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0145"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  phosphate-buffered saline  PDGFRA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0155"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  platelet-derived growth factor receptor–α  SPG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0165"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  sympathetic prevertebral ganglia  SPN"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0175"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  sympathetic postganglionic neuron  TH"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0185"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  tyrosine hydroxylase  TNT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0195"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  0.1M Tris HCl, 1.5% NaCl, and 0.3% Triton X-100
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