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Microbial Community Heterogeneity Within Colorectal Neoplasia and its Correlation With Colorectal Carcinogenesis

Authors:	Weixin Liu Xiang Zhang Hongzhi Xu Shengmian Li Harry Cheuk-Hay Lau Qiongyun Chen Bin Zhang Liuyang Zhao Huarong Chen Joseph Jao-Yiu Sung Jun Yu

Institution:	1. Institute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Shenzhen Research Institute, Sha Tin, New Territories, Hong Kong;2. Institute for Microbial Ecology, School of Medicine, Xiamen University, Department of Gastroenterology, Zhongshan Hospital, Xiamen University, Xiamen, China;3. Department of Gastroenterology, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China

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Keywords:	Colorectal Cancer Colorectal Carcinogenesis Microbial Community Intra-Neoplasia Heterogeneous Microbiota CRC"} {"#name":"keyword" "$":{"id":"kwrd0035"} "$$":[{"#name":"text" "_":"colorectal cancer %CV"} {"#name":"keyword" "$":{"id":"kwrd0045"} "$$":[{"#name":"text" "_":"percent coefficient of variation DMA"} {"#name":"keyword" "$":{"id":"kwrd0055"} "$$":[{"#name":"text" "_":"difference in mean abundance FD"} {"#name":"keyword" "$":{"id":"kwrd0065"} "$$":[{"#name":"text" "_":"fold-difference FDV"} {"#name":"keyword" "$":{"id":"kwrd0075"} "$$":[{"#name":"text" "_":"fold-difference in average percent coefficient of variation HVM"} {"#name":"keyword" "$":{"id":"kwrd0085"} "$$":[{"#name":"text" "_":"high-variable microbe MSI"} {"#name":"keyword" "$":{"id":"kwrd0095"} "$$":[{"#name":"text" "_":"microsatellite instability NA"} {"#name":"keyword" "$":{"id":"kwrd0105"} "$$":[{"#name":"text" "_":"normalized abundance OTU"} {"#name":"keyword" "$":{"id":"kwrd0115"} "$$":[{"#name":"text" "_":"operational taxonomic unit PCR"} {"#name":"keyword" "$":{"id":"kwrd0125"} "$$":[{"#name":"text" "_":"polymerase chain reaction PERMANOVA"} {"#name":"keyword" "$":{"id":"kwrd0135"} "$$":[{"#name":"text" "_":"permutational multivariate analyses of variance RI"} {"#name":"keyword" "$":{"id":"kwrd0145"} "$$":[{"#name":"text" "_":"risk index rRNA"} {"#name":"keyword" "$":{"id":"kwrd0155"} "$$":[{"#name":"text" "_":"ribosomal RNA
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