| 新生儿高胆红素血症血清总胆汁酸测定的临床价值探讨 |
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| 引用本文： | 杨春云,王春霞,邱清芳. 新生儿高胆红素血症血清总胆汁酸测定的临床价值探讨[J]. 医学检验与临床, 2005, 16(5): 10-11 |
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| 作者姓名： | 杨春云 王春霞 邱清芳 |
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| 作者单位： | 1. 莱州市人民医院检验科,莱州,26140
2. 烟台市莱州荣军医院,莱州,261400 |
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| 摘 要： | 目的探讨血清总胆汁酸(TBA)测定对新生儿高胆红素血症患儿肝功能损伤的临床价值。方法采用循环酶速率法检测187例新生儿高胆红素血症患儿血清TBA水平。结果新生儿高未结合胆红素血症组与对照组差异无显著性;高结合胆红素血症组的血清TBA水平明显高于对照组。回顾性病例分析显示,高未结合胆红素血症患儿无肝功能损伤,病情转归良好(100%痊愈);高结合胆红素血症患儿存在肝功能损伤或胆汁淤积,病情转归不佳,68.18%好转,31.82%未愈。结论当常规肝功能指标改变不明显时,血清TBA检测是一项新生儿病理性黄疸患儿较为灵敏的肝实质损伤的指标。
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| 关 键 词： | 新生儿 胆汁酸 高胆红素血症 |
Study on the clinical value of changes of serum total bile acids in newborn Hyperbilirubinemia |
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| Yang Chunyun,Wang Chunxia,Qiu Qingfang. Study on the clinical value of changes of serum total bile acids in newborn Hyperbilirubinemia[J]. Medical Laboratory Science and, 2005, 16(5): 10-11 |
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| Authors: | Yang Chunyun Wang Chunxia Qiu Qingfang |
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| Affiliation: | Yang Chunyun Wang Chunxia Qiu Qingfang The people's hospital of Laizhou city,Shandong 261400.P.R.China |
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| Abstract: | Objective To study the clinical diagnostic meaning of TBA test for evaluation of infant's hypohepatia.Methods 187 infant's serum TBA were tested by enzymatic cycling method.Results There is not remarkable difference between the group of unconjugated hyperbilirubinemia and the comparison.The serum TBA of conjugated hyperbilirubinemia are markedly higher than comparison.Case review shows that the infant with unconjugated hyperbilirubinemia but no hypohepatia has good prognosis(100% cure);The infant with conjugated hyperbilirubinemia and hypohepetia or cholestasis has bad prognosis.Conclusion The test of serum TBA is a sensitive item to identify liver essential trauma for infant with pathologic jaundice. |
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| Keywords: | Newbron Total bile acids Hyperbilirubinemia |
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