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Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53
Authors:Banu Sakhila K  Stanley Jone A  Lee Jehoon  Stephen Sam D  Arosh Joe A  Hoyer Patricia B  Burghardt Robert C
Affiliation:
  • a Department of Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA
  • b Department of Physiology, University of Arizona, Tucson, AZ 85724-5051, USA
  • Abstract:
    Keywords:CrVI, Hexavalent chromium   CrIII, Trivalent chromium   TUNEL, Terminal deoxynucleotidyl transferase dUTP nick end labeling   Bcl-2, B-cell lymphoma 2   Bcl-XL, B-cell lymphoma-extra large   BAX, BCL2-associated X protein   BAD, Bcl-xL/Bcl-2-Associated Death Promoter   HSP70/HSP90, Heat shock proteins-70 and -90   MAP Kinase, Mitogen-activated protein (MAP) kinase   ERK, Extracellular-signal-regulated kinase   JNK, c-Jun N-terminal kinase   PARP, Poly (ADP-ribose) polymerase
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