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| 肺动脉高压右心室流出道血流频谱与右心功能的关系 | |
| 引用本文： | 刘彤,程宇彤,Forfia Paul,何怡华,徐洁,王苏,陶英,高玉龙,高云,米玉红,刘双.肺动脉高压右心室流出道血流频谱与右心功能的关系[J].心肺血管病杂志,2011,30(2):129-132,139. |
| 作者姓名： | 刘彤 程宇彤 Forfia Paul 何怡华 徐洁 王苏 陶英 高玉龙 高云 米玉红 刘双 |
| 作者单位： | 1. 首都医科大学附属安贞医院-北京市心肺血管疾病研究所抢救中心,北京,100029 2. 美国宾夕法尼亚大学心脏中心,心力衰竭/心脏移植/心室辅助项目 3. 首都医科大学附属安贞医院-北京市心肺血管疾病研究所超声科,北京,100029 4. 首都医科大学附属安贞医院-北京市心肺血管疾病研究所呼吸科,北京,100029 |
| 摘 要： | 目的:探讨肺动脉高压患者右心室流出道血流频谱收缩期切迹与右心室收缩功能的关系。方法:收集88例不同原因导致的肺动脉高压患者的临床、血流动力学及超声心动图的资料。根据右心室流出道血流频谱形态分为无切迹组(no notch;NN)、收缩晚期切迹组(late systolic notch;LSN)、收缩中期切迹组(mid-systolic notch;MSN)。以M型超声在心尖四腔心切面三尖瓣环收缩期位移(TAPSE)数值表示右心室收缩功能。结果:肺血管阻力(PVR)在MSN组最高(9.2±3.5)WU,P<0.001,而LSN组为(5.7±3.1)WU,NN组为(3.3±2.4)WU。与LSN组和NN组相比,MSN组TAPSE明显缩短MSN=(1.6±0.5)cm,LSN=(1.9±0.6)cm,NN=(2.2±0.6)cm,P<0.05]。右心室流出道多普勒加速时间(AT)在MSN组最短(MSN=67±21,LSN=79±18,NN=113±29;MSN vs.NN,P<0.01;MSN vs.LSN,P<0.01;LSN vs.NN,P<0.05)。结论:右心室流出道血流多普勒频谱收缩期切迹可能提示严重的肺动脉高压(PAH)和右心功能不全。 |
| 关 键 词： | 肺动脉高压 右心室流出道血流多普勒频谱 右心室功能 血流动力学 |
Doppler notching and hemodynamic in pulmonary hypertension |
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| LIU Tong,CHENG Yutong,Forfia Paul,HE Yihua,XU Jie,WANG Su,TAO Yin,GAO Yulong,GAO Yun,MI Yuhong,LIU Shuang.Doppler notching and hemodynamic in pulmonary hypertension[J].Journal of Cardiovascular and Pulmonary Diseases,2011,30(2):129-132,139. | |
| Authors: | LIU Tong CHENG Yutong Forfia Paul HE Yihua XU Jie WANG Su TAO Yin GAO Yulong GAO Yun MI Yuhong LIU Shuang |
| Institution: | LIU Tong,CHENG Yutong,Forfia Paul,HE Yihua,XU Jie,WANG Su,TAO Yin,GAO Yulong,GAO Yun,MI Yuhong,LIU Shuang Depart-ment of Cardiology,Capital Medical University Affiliated Beijing Anzhen Hospital,Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing 100029,China |
| Abstract: | Objective:We investigated whether simple visual assessment of FVERVOT(the right ventricular outflow tract Doppler flow velocity envelop) morphology aids in right ventricular function among a referral PH cohort.Methods:We reviewed hemodynamics,echocardiography,and clinical data for 88 patients referred for PH.The FVERVOTwas categorized as normal(no notch;NN),late systolic notch(LSN) or mid-systolic notch(MSN).Results:The pulmonary vascular resistance(PVR) was highest in the MSN group (9.2±3.5)WU,P<0.001) vs.the LSN(5.7±3.1) WU]and NN(3.3±2.4) WU groups.The MSN group had severe RV dysfunction TAPSE(1.6±0.5) cm relative to the LSN and NN groups TAPSE(1.9±0.6) cm vs.(2.2±0.6) cm;both P<0.05].Conclusion:MSN is associated with the most severe right heart dysfunction. |
| Keywords: | Pulmonary hypertension The right ventricular outflow tract Doppler flow velocity envelope Right ventricular function Hemodynamic |
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