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急性等溶血液稀释在非停跳冠状动脉搭桥术中的血液保护效果
引用本文:张亮,卿恩明,卢家凯,董秀华,胡适. 急性等溶血液稀释在非停跳冠状动脉搭桥术中的血液保护效果[J]. 心肺血管病杂志, 2011, 30(2): 140-143. DOI: 10.3969/j.issn.1007-5062.2011.02.013
作者姓名:张亮  卿恩明  卢家凯  董秀华  胡适
作者单位:首都医科大学附属北京安贞医院-北京市心肺血管疾病研究所,麻醉科,北京,100029
摘    要:
目的:评价急性等溶血液稀释(ANH)在非停跳冠状动脉搭桥术中血液保护的临床效果。方法:选择非停跳冠状动脉搭桥术患者60例,随机分为血液稀释组(A组,n=30例)和对照组(C组,n=30例)。A组于麻醉平稳后经中心静脉采血,同时输入等容量胶体液,将红细胞压积稀释到30%。血液稀释后各时点记录血流动力学及Hb变化情况。记录2组患者术前,术后4 h、24 h、48 h红细胞血小板等变化情况,同时记录血浆用量、浓缩红细胞用量、术后4 h,24 h引流量等指标。结果:2组患者术前一般情况差异无统计学意义(P>0.05)。A组血浆及浓缩红细胞用量显著低于C组(P<0.05)。结论:在非停跳冠状动脉搭桥术患者应用适度ANH可减少术中、术后异体血液用量。

关 键 词:血液稀释  非停跳冠状动脉搭桥术  血液输注  冠状动脉疾病

Evaluation of acute normovolemic hemodilution on blood conservation during off-pump coronary artery bypass grafting surgery
ZHANG Liang,QING Enming,LU Jiakai,DONG Xiuhua,HU Shi. Evaluation of acute normovolemic hemodilution on blood conservation during off-pump coronary artery bypass grafting surgery[J]. Journal of Cardiovascular and Pulmonary Diseases, 2011, 30(2): 140-143. DOI: 10.3969/j.issn.1007-5062.2011.02.013
Authors:ZHANG Liang  QING Enming  LU Jiakai  DONG Xiuhua  HU Shi
Affiliation:ZHANG Liang,QING Enming,LU Jiakai,DONG Xiuhua,HU Shi Department of Anesthesiology,Capital Medical University affiliated Beijing Anzhen Hospital,Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing 100029,China
Abstract:
Objective:To evaluate acute normovolemic hemodilution(ANH) on blood conservation during off-pump coronary artery bypass grafting surgery(OPCABG).Methods:Sixty patients scheduled for off-pump coronary artery bypass surgery were randomly assigned to ANH group(A group,30 patients) or control group(C group,30 patients).In the ANH group,following anesthesia induction,blood was withdrawn from a central vein by gravity,in parallel,6% hydroxyethyl starch(HAES) was infused to maintain normovolemia.The hemodynamics m...
Keywords:Hemodilution  Off-pump coronary artery bypass surgery  Blood transfusion  Coronary artery disease  
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