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Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING
Authors:Run Fang  Qifei Jiang  Yukun Guan  Pengfei Gao  Rui Zhang  Zhen Zhao  Zhengfan Jiang
Affiliation:1. Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, School of Life Sciences, Peking University, Beijing 100871, China;2. Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
Abstract:
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  • Keywords:cGAS-STING  sulfated glycosaminoglycans (sGAGs)  anti-viral innate immunity  STING-associated vasculopathy with onset in infancy (SAVI)
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