首页 | 本学科首页   官方微博 | 高级检索  
     


A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus
Authors:Bronwyn M. Gunn  Richard Lu  Matthew D. Slein  Philipp A. Ilinykh  Kai Huang  Caroline Atyeo  Sharon L. Schendel  Jiyoung Kim  Caitlin Cain  Vicky Roy  Todd J. Suscovich  Ayato Takada  Peter J. Halfmann  Yoshihiro Kawaoka  Matthias G. Pauthner  Mambu Momoh  Augustine Goba  Lansana Kanneh  Galit Alter
Affiliation:1. Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA;2. Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, TX, USA;3. Galveston National Laboratory, Galveston, TX, USA;4. La Jolla Institute for Immunology, La Jolla, CA, USA;5. Research Center for Zoonosis Control, Hokkaido University, Sapporo, Japan;6. Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin – Madison, Madison, WI, USA;7. Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA, USA;8. Viral Hemorrhagic Fever Program, Kenema Government Hospital, Kenema, Sierra Leone;9. Scripps Research Translational Institute, La Jolla, CA, USA;10. Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA, USA;11. Ministry of Health and Sanitation, Freetown, Sierra Leone;12. Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA;13. Department of Microbiology and Immunology, University of Texas Medical Branch at Galveston, Galveston, TX, USA
Abstract:
><ol class=
  • Download : Download high-res image (202KB)
  • Download : Download full-size image
  • Keywords:antibody engineering  Ebola virus  Fc effector function  humoral immunity  infectious diseases  monoclonal antibody therapeutics  ADCC  phagocytosis  complement
    本文献已被 ScienceDirect 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号