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SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2
Authors:Qiao Lu  Jia Liu  Shuai Zhao  Maria Florencia Gomez Castro  Maudry Laurent-Rolle  Jianbo Dong  Xiaojuan Ran  Payal Damani-Yokota  Hongzhen Tang  Triantafyllia Karakousi  Juhee Son  Maria E. Kaczmarek  Ze Zhang  Stephen T. Yeung  Broc T. McCune  Rita E. Chen  Fei Tang  Xianwen Ren  Jun Wang
Affiliation:1. Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA;2. The Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA;3. Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China;4. Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China;5. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA;6. Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA;7. Ab Studio, Inc., Hayward, CA 94545, USA;8. Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA;9. Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA;10. Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA;11. BIOPIC, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing 100871, China;12. Joint Research Center of Hangzhou First Hospital Group and Westlake University, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China;13. Kactus Biosystems Co., Ltd., Shanghai 201114, China;14. Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;15. Department of Computer Science, Purdue University, West Lafayette, IN 47907, USA;16. Division of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, NY 10016, USA
Abstract:
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  • Keywords:SARS-CoV-2  COVID-19  DC-SIGN  L-SIGN  LSECtin  ASGR1  CLEC10A  TTYH2  myeloid cells  proinflammatory responses
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