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Small-molecule inhibitors of ubiquitin-specific protease 7 enhance type-I interferon antiviral efficacy by destabilizing SOCS1 |
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| Authors: | Yukang Yuan Ying Miao Chenhua Zeng Jin Liu Xiangjie Chen Liping Qian Xiaofang Wang Feng Qian Zhengyuan Yu Jun Wang Guanghui Qian Qian Fu Haitao Lv Hui Zheng |
| Institution: | 1. Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China
These three authors contributed equally to this work.;2. Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, China;3. Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China;4. The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, China;5. Department of Oncology, the First Affiliated Hospital of Soochow University, Suzhou, China;6. Department of Intensive Care Medicine, the First Affiliated Hospital of Soochow University, Suzhou, China;7. Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China;8. Soochow University Library, Suzhou, China |
| Abstract: | |
| Keywords: | antiviral activity interferon small-molecule inhibitor suppressor of cytokine signaling 1 ubiquitin-specific protease 7 |