运动干预对2型糖尿病患者生活质量的影响

目的 探讨运动干预对2型糖尿病(T2DM)患者生活质量(QOL)的影响.方法 选择200例T2DM患者,随机分为试验组和对照组各100例,对照组予以常规的降糖治疗;试验组除了对照组的治疗外,每天进行强化运动治疗2次.6个月后,162例患者完成了试验观察,每组81例,比较2组患者干预前后QOL得分并分析影响QOL得分变化的临床因素.结果 干预6个月后,试验组和对照组的生理维度、心理维度、社会维度、满意度、普适分和总分均存在处理主效应[(58.93±5.19)分,(46.85±9.26)分; (59.19±3.57)分,( 47.87±9.04)分; (57.20±5.36)分,(47.67±9.25)分;(59.80±5.93)分,(47.03±8.64)分;(235.12±13.60 )分,(189.42±25.31)分;(293.24±18.49)分,(236.79±31.83)分;均P＜0.01],也存在时间主效应(均P＜0.01)和交互作用(均P＜0.01);生活质量总分干预前后的差值与体重指数、空腹血糖、糖化血红蛋白及餐后血糖干预前后的差值有关;试验组的直接成本-效果比低于对照组.结论 运动干预有助于改善T2DM患者的QOL,降低直接成本效果比.

Study of exercise intervention on quality of life in type 2 diabetic patients

ObjectiveTo explore the effects of exercise intervention on quality of life( QOL)in type 2 diabetic patients. Methods200 patients , who were type 2 diabetes mellitus, were divided into the experimental group and the control group randomly. All the patients in the control group were given a standard treatment of lowering blood sugar. Those in the experimental group strengthened physical exercise twice a day extraordinarily. 162 patients completed the experiment observations and each group were 81 patients after 6 months.The scores of QOL were assessed before and after intervention,and analyzed the clinical factors which affected QOL.ResultsThere were significant differences of the dimensions including physical, social, psychological, satisfaction, universal and total between the two groups after intervention for 6 months[(58.93±5.19)vs(46.85±9.26); (59.19±3.57)vs( 47.87±9.04); (57.20±5.36)vs(47.67±9.25); (59.80±5.93)vs(47.03±8.64); (235.12±13.60 )vs (189.42±25.31); (293.24±18.49)vs (236.79±31.83);all P＜0.01].There were the main effects of time (all P＜0.01) and intervention(all P＜0.01).The difference of the total scores on the quality of life before and after intervention was related to the difference of body mass index, fasting glucose, glycolated hemoglobin and postmeal glucose. The direct cost-effectiveness in the experimental group were lower than those in the control group.ConclusionThe exercise intervention contributes to improve the quality of life of type 2 diabetic patients;and reduce the direct cost-effectiveness of lowering blood sugar of the patients.