脾虚证胃粘膜组织细胞病理学研究

目的：探索脾虚证胃粘膜相，胃粘膜病变的程度与脾虚证型的关系，方法：取经检测排除心，肺，肝，胆，胰，肾及肠等容质性疾病的１８８例脾虚证患者胃粘膜，应用光学显微镜，扫描电镜，透射电镜和组织化学染色，进行组织病理学，亚细胞超微结构检测，结果：脾气虚证和脾阳虚证胃粘膜既可有器质性病变存在（Ｇ型）也可无器质性病变存在（Ｆ型）；脾阴虚型和脾虚气证胃粘膜的有器质性病变存在，且病变程度也较Ｇ脾气虚证与Ｇ脾阳虚证型

Histocytopathological Study on Gastric Mucosa of Spleen Deficiency Syndrome

OBJECTIVE: To explore the pictures of gastric mucosa of Spleen deficiency syndrome, and the relationship between the degree of pathological changes of gastric mucosa and types of Spleen deficiency syndrome. METHODS: One hundred and eighty-eight Spleen deficiency patients with organic diseases of heart, lung, liver, gallbladder, pancreas, intestine and kidney excluded were examined their gastric mucosa. Tests of histopathology and subcellular ultrastructure were conducted by using optical microscope, electron scanning microscope, electron transmission microscope and histochemical staining methods. RESULTS: The gastric mucosa of Spleen Qi deficiency and Spleen Yang deficiency patients could either be affected with organic lesion (type G) or unaffected (type F); the gastric mucosa of Spleen Yin deficiency and Spleen deficiency with Qi stagnation were both affected by gastric lesions, and the degree of their lesions was more serious than that of Spleen Qi deficiency of type G and Spleen Yang deficiency of type G, P < 0.05-0.01. CONCLUSION: Pathological changes did not necessarily occur in the gastric mucosa of Spleen deficiency patients; the degree of pathological changes was relevant with the evolution of Spleen deficiency types.