老年非小细胞肺癌合并肺部感染的临床特点及危险因素分析

目的 探讨老年非小细胞肺癌合并肺部感染的临床特点及危险因素.方法 分析2017年12月至2020年12月我院收治的111例非小细胞肺癌患者的临床资料.以细菌培养鉴定计算感染率,根据是否合并肺部感染分为合并组、未合并组,分析临床特点以及影响非小细胞肺癌合并肺部感染的独立危险因素.结果 111例非小细胞肺癌患者中,合并肺部...

Analysis of clinical features and risk factors of elderly patients with non-small cell lung cancer complicated with lung infection

Objective To explore the clinical characteristics and risk factors of elderly patients with non-small cell lung cancer(NSCLC)complicated with lung infection.Methods Clinical data of 111 patients with NSCLC admitted to our hospital from December 2017 to December 2020 were collected.The infection rate was calculated through bacterial culture identification.The patients were divided into a complicated group and an uncomplicated group according to whether patients were complicated with lung infection.The clinical characteristics were analyzed.The logistic regression model was used to analyze the independent risk factors ofthe complicated lung infection.Results Amongthe 111 patients,45(40.54%)were complicated with lung infection,and 66(59.46%)were not complicated with lung infection.A total of 89 pathogenic bacteria were isolated from the 45 patients.Amongthe pathogenic bacteria,51 strains(57.30%)were gram-negative bacteria.Moreover,35 strains(39.33%)were gram-positive bacteria,and 3 strains(3.37%)were fungi.There were statistically significant differences in tumor type,tumor diameter,TNM staging,D-dimer(D-D),hemoglobin(Hb),white blood cells(WBC)count,and carcinoembryonic antigen(CEA)levels between the two groups(P<0.05).Tumor diameter>4cm,high TNM staging(Stage III~IV),D-D>500g/L,adenocarcinoma,Hb<100g/L,and CEA>10nh/M were independent risk factors for NSCNCpatients complicated with pulmonary infection.Conclusion High TNM stage,adenocarcinoma,Hb,D-D,WBC count,and CEA levels are risk factors for lung infection in patients with NSCLC.