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von Willebrand因子与稳定冠心病
引用本文:殷兆芳,方唯一. von Willebrand因子与稳定冠心病[J]. 心血管病学进展, 2010, 31(1): 41-43. DOI: 10.3969/j.issn.1004-3934.2010.01.013
作者姓名:殷兆芳  方唯一
作者单位:1. 上海交通大学医学院附属第九人民医院心脏科,上海,200011
2. 上海交通大学附属胸科医院心脏科,上海,200030
摘    要:
早期大量研究揭示了von Willebrand因子的生物学特点、结构和功能,近期研究发现von Willebrand因子可能在稳定冠心病发病、剪切力机制诱导血小板聚集、血栓形成,以及药物和介入治疗(包括支架置入等)方面有重要作用。

关 键 词:von  Willebrand因子  剪切力  血栓形成  支架  冠心病

von Willebrand Factor and Stable Coronary Artery Disease
YIN Zhao-fang,FANG Wei-yi. von Willebrand Factor and Stable Coronary Artery Disease[J]. Advances in Cardiovascular Diseases, 2010, 31(1): 41-43. DOI: 10.3969/j.issn.1004-3934.2010.01.013
Authors:YIN Zhao-fang  FANG Wei-yi
Affiliation:YIN Zhao-fang, FANG Wei-yi (1. Deparment of Cardiology, Shanghai Ninth People's Hospital Affiliated to School of Medicine, Shanghai Jiaotong University Shanghai 200011, China ;2. Deparment of Cardiology, Shanghai Chest Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200030, China )
Abstract:
Previous studies have proven the structure,function,and biological characteristics of the von Willebrand factor. Additionally,many new studies have found that von Willebrand factor may play a great role in stabilizing coronary artery disease,through platelet aggravation induced by shear stress,thrombosis,medical therapy and percutaneous coronary intervention.
Keywords:von  von Willebrand factor  shear stress  thrombosis  stent  coronary rtery disease
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