| RNAi技术在肿瘤研究领域中的进展 |
| |
| 引用本文： | 怀娜,马秀梅. RNAi技术在肿瘤研究领域中的进展[J]. 内蒙古医学杂志, 2009, 41(5): 573-576 |
| |
| 作者姓名： | 怀娜 马秀梅 |
| |
| 作者单位： | 内蒙古医学院,内蒙古,呼和浩特,010059;内蒙古医学院病理科,内蒙古,呼和浩特,010059 |
| |
| 基金项目： | 国家自然科学基金,教育部春晖计划项目,博士启动金项目 |
| |
| 摘 要： | RNA干扰（RNAinterference,RNAi）是由双链RNA（double stranded RNA,dsRNA）分子介导的序列特异性转录后基因沉默（post-transcriptional gene silencing,PTGS）过程。RNAi最主要的功能是它可以调节和关闭基因的表达进而调控细胞的各种高级生命活动,利用RNAi技术可以探索肿瘤的病理机制,为肿瘤的治疗提供一条新的有效途径。本文就RNAi技术及其在肿瘤研究中的应用作一综述。
|
| 关 键 词： | RNA干扰 肿瘤 基因沉默 |
RNA Interference Technology and Neoplasm |
| |
| HUAI Na,MA Xiu-mei. RNA Interference Technology and Neoplasm[J]. Inner Mongolia Medical Journal, 2009, 41(5): 573-576 |
| |
| Authors: | HUAI Na MA Xiu-mei |
| |
| Affiliation: | 1.Post Graduate 2007;Inner Mongolia Medical College;Huhhot 010059 China;2.Department of Pathology;The Affiliated Hospital of Inner Mongolia Medical College;Huhhot 010059 China |
| |
| Abstract: | RNA interference(RNAi) is the sequence-specific post-transcriptional gene silencing(PTGS) process mediated by double-stranded RNA(dsRNA) molecules.RNAi's most important feature is that itcan regulate gene expression and then regulate cell's various advanced life activities.RNAi technology can be used to explore the pathological mechanism for the neoplasm,and provide a radical new and effective way to cure neoplasm.This article eill review the RNAi technology and the applications in tumor. |
| |
| Keywords: | RNA interference Neoplasm Gene silencing |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
