超小剂量瑞芬太尼复合异丙酚在日间无痛人流术中效果及离院时间的观察

目的：比较超小剂量瑞芬太尼复合异丙酚麻醉用于日间无痛人流术的效果及对离院时间的影响。方法：选择行无痛人流术的早孕妇女200例．随机分为瑞芬太尼复合异丙酚组（A组）和单纯异丙酚组（B组）各100例。A组：瑞芬太尼0．3ug／kg．异丙酚1．5mg／kg。B组：异丙酚2mg／kg。分别记录术前，术中和术后的HR．SBP、DBP和SpO2及异丙酚总量、苏醒时间、以及离院时间。结果：A组术前．术中．术后的SPO2没有显著差异．平均动脉压术前、术后没有显著差异（P〉0．05），术中与术前、术后有显著差异（P〈0．01）。心率术前、术后没有显著差异（P〉0．05），术中与术前、术后有显著差异（P〈0．01）。B组术前、术后SPO2没有显著差异．术中与术前．术后有显著差异（P〈0．01）。平均动脉压术前．术后没有显著差异（P〉0．05），术中与术前、术后有显著差异（P〈0．01）。术前、术中、术后的HR没有显著差异（P〉0．05）。丙泊酚总量（P〈0．01），清醒时闻（P〈0．01）离院时间（P〈0．01）．均有显著性差异。结论：超小剂量瑞芬太尼复合异丙酚用于无痛人流术效果好．安全可行，能减少病人留院时间．加快日间手术室的运转。但术中需严密监测呼吸、循环并加强管理。

Observation the Effects and the Time of Leaving Hospital when Ultra-low-dose Remifentanil and Propofol were Used in the Day- painless -abortion

Objective： Compare with the effects and the time of leaving hospital when one used super doses of Remifentanil compound propofol and other used propofol in the Day-painless-abortion. Methods： Choose 200 women who were made Day-painless-abortion.The results were randomly divided into Remifentanil compound prepofol group （group A） and propofol group （group B）. A： Remifentanil 0.3ug/kg, propofol 1.5mg/kg. B： the propofol 2mg/kg. Record thepreoperative,intraoperative and postoperative SBP, HR, DBP SpO2, the total propofol ,the time of awaking and the time of awaking to leave the hospital. Results： A group of preoperative,intraoperative and postoperative SPO2 no significant difference. The mean arterial pressure（MAP） of the preoperative and postoperative no significant difference （P〉0.05）, but the MAP ofintraoperative was different between postoperative andpreoperative was significant （P〈0.01）. The heart rate（HR） of the preoperative, intraoperative and postoperative were no significant difference （P〉0.05）, but the HR ofintraoperative is different from postoperative and preoperative were significant （P〈0.01）. B group of preoperative and postoperative SPO2 no significant difference. The SPO2 of intraoperative was different between preoperative and postoperative was significant difference （P〈0.01）, the MAP of preoperative and postoperative no significant difference （P〉0.05）, but the MAP ofintraoperative was different between postoperative and preoperative was significant （P〈0.Ol）. the HR of preoperative,intraoperative and postoperative were no significant difference （P〉0.05）. Prepofol dosage （P〈0.01）, waking time （P〈0.01）,the time of from awaking to leave the hospital. （P〈0.01）, all have significant differences. Conclusion： The effect of Ultra-low-dose remifentanil compound propofol was good in painless abortion ,that safe and feasible, which can reduce the time of patients leave to hospital, Accelerate daytime work. But should closely monitor of breathing, circulation and strengthen management.