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Current concept and future research directions of mild cognitive impairment
Authors:Hiroyuki ARAI
Institution:Department of Geriatric and Complementary Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
Abstract:Alzheimer's disease (AD) generally begins with mild memory problems which occur in an insidious manner and progresses to the development of multiple cognitive impairments. There is a ‘gray’ area between what is classified as ‘normal’ and what is classified as ‘dementia’, currently called mild cognitive impairment (MCI). In this article, a case of MCI is described, and the diagnosis, assessment, subclassification (pre‐Alzheimer type and white matter lesion type) and future therapeutic plans for MCI are reviewed.
Keywords:cerebrospinal fluid tau  dementia  early diagnosis  early intervention  periventricular white matter lesion
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