Aerosol propellant interference with clinical mass spectrometers |
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| Authors: | Dr Evan D. Kharasch MD PhD Murali Sivarajan MB BS |
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| Affiliation: | 1. From the Departments of Anesthesiology and Medicinal Chemistry, University of Washington and Veterans Affairs Medical Center, Seattle, WA
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| Abstract: | ![]()
Metered dose inhalers containing halogenated propellants may interfere with mass spectrometer quantitation of halogenated inhalation anesthetics. We identify the propellant(s) in a commercially available metered dose inhaler that caused erroneous mass spectrometer readings. In addition, we identify the causes of different types of interference in different mass spectrometers. |
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