| 星点设计-效应面法优化甘草水提工艺 |
| |
| 引用本文： | 古川.星点设计-效应面法优化甘草水提工艺[J].中国药师,2015(8):1253-1255. |
| |
| 作者姓名： | 古川 |
| |
| 作者单位： | 陕西中医学院/陕西省中药资源产业化协同创新中心/陕西省中药基础与新药研究重点实验室 陕西咸阳 712046;陕西中医学院/陕西省中药资源产业化协同创新中心/陕西省中药基础与新药研究重点实验室;陕西中医学院/陕西省中药资源产业化协同创新中心/陕西省中药基础与新药研究重点实验室;陕西中医学院/陕西省中药资源产业化协同创新中心/陕西省中药基础与新药研究重点实验室;陕西中医学院/陕西省中药资源产业化协同创新中心/陕西省中药基础与新药研究重点实验室;陕西中医学院/陕西省中药资源产业化协同创新中心/陕西省中药基础与新药研究重点实验室;陕西中医学院/陕西省中药资源产业化协同创新中心/陕西省中药基础与新药研究重点实验室 |
| |
| 基金项目： | 国家自然科学基金项目（编号：81373978） |
| |
| 摘 要： | 摘 要 目的： 运用星点设计 效应面法对甘草水提工艺进行优化。方法: 用HPLC法测定甘草苷、甘草酸含量，以甘草苷、甘草酸含量和干膏收率为综合评价指标，以加水倍量、提取时间为自变量，综合评价指标为因变量，采用Design-Expert 8.06对试验数据进行多元线性回归及二项式拟合，用效应面法优选最佳水提工艺，并对结果进行预测分析。结果: 最佳水提工艺为12倍量水，提取2次，每次90 min，提取预测值与理论值偏差为-1.72%，二项式拟合复相关系数r=0.979 7。结论: 星点设计 效应面法优化甘草水提工艺，简便可行，预测性较高；为后续应用膜分离纯化提供最佳提取工艺。
|
| 关 键 词： | 甘草 星点设计 效应面法 水提工艺 |
| 收稿时间： | 2015/3/18 0:00:00 |
| 修稿时间： | 2015/4/29 0:00:00 |
Optimization of Water Extraction Process for Glycyrrhiza by Central Composite Design /Response Surface Methodology |
| |
| Gu Chuan.Optimization of Water Extraction Process for Glycyrrhiza by Central Composite Design /Response Surface Methodology[J].China Pharmacist,2015(8):1253-1255. |
| |
| Authors: | Gu Chuan |
| |
| Institution: | Shaanxi University of Chinese Medicine/Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Xianyang 712046, China;Shaanxi University of Chinese Medicine/Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research;Shaanxi University of Chinese Medicine/Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research;Shaanxi University of Chinese Medicine/Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research;Shaanxi University of Chinese Medicine/Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research;Shaanxi University of Chinese Medicine/Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research;Shaanxi University of Chinese Medicine/Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research |
| |
| Abstract: | |
| |
| Keywords: | |
|
| 点击此处可从《中国药师》浏览原始摘要信息 |
| 点击此处可从《中国药师》下载免费的PDF全文 |
