Recent advances in the application of indoles in multicomponent reactions |
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| Authors: | Ghodsi Mohammadi Ziarani Razieh Moradi Tahereh Ahmadi Negar Lashgari |
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| Affiliation: | Department of Chemistry, Alzahra University, Tehran Iran, Fax: +98 21 88041344, +98 21 88041344 |
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| Abstract: | Indoles are some of the most versatile and common nitrogen-based heterocyclic scaffolds and are frequently used in the synthesis of various organic compounds. Indole based compounds are very important among heterocyclic structures due to their biological and pharmaceutical activities. The last decade, in particular, has witnessed considerable activity towards the synthesis of indole derivatives due to the possibilities for the design of polycyclic structures by the incorporation of multiple fused heterocyclic scaffolds in an attempt to achieve promising new heterocycles with chemical and biomedical relevance. In this study, we provide an overview on recent applications of indole in the multicomponent reactions for the synthesis of various heterocyclic compounds during the period of 2012 to 2017.An overview on recent applications of indoles in multicomponent reactions for the synthesis of heterocyclic compounds is provided. |
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