| 普伐他汀治疗肾病综合征高脂血症35例临床分析 |
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| 引用本文： | 连祖民 李启田 等. 普伐他汀治疗肾病综合征高脂血症35例临床分析[J]. 国外医学:心血管疾病分册, 2003, 30(1): 37-38 |
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| 作者姓名： | 连祖民 李启田 等 |
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| 作者单位： | 山东省东营市胜利石油管理局中心医院肾内科 257034(连祖民，李启田，肖英)，山东省东营市胜利石油管理局中心医院肾内科 257034(张洪源) |
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| 摘 要： | 目的：总结普伐他汀治疗肾病综合征高脂血症的疗效。方法：对35例伴肮脂血症的肾病综合征患者在用强的松、利尿、降压、抗凝治疗的同时，每晚给予普伐他汀10mg，连续1个月。其间停用其他降脂药。治疗前后测定病人血清CH、TG、LDL－C和GDL－C。结果：治疗1个月后血CH、TG、LDL－C均显著下降（P＜0．01），HDL－C则升高（P＜0．05）。未见有不良反应.结论：普伐他汀有显著降血脂作用，特别适用于治疗高胆固醇血症及LDL－C升高者。
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| 关 键 词： | 普伐他汀 治疗 肾病综合征 高脂血症 临床分析 |
Efficacy of pravastatin in the treatmwnt of hyperlipedemia in 35 patients with nephrotic syndrome |
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| LIAN Zumin LI Qitian XIAO Ying,et al.. Efficacy of pravastatin in the treatmwnt of hyperlipedemia in 35 patients with nephrotic syndrome[J]. , 2003, 30(1): 37-38 |
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| Authors: | LIAN Zumin LI Qitian XIAO Ying et al. |
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| Affiliation: | LIAN Zumin LI Qitian XIAO Ying,et al. Dept of Nephrology,Hospital of Shengli Petrol Administration,Dongying,Shandong 257034 |
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| Abstract: | Objective: To investigate the efficacy of pravastatin in the treatment of hyperlipidemia in patients with nephrotic syndrome. Methods: Thirty five patients with nephrotic syndrome complicated with hyperlipidemia received in addition to the basic prednisone, diuretic, antihypertensive and anticoagulant treatment, pravastatin sodium 10mg qn for 1 month. Serum CH, TG, LDL-C and HDL-C of the patients were determined before and 1 month after treatment. Results: The serum CH, TG, LDL-C of patients were decreased significantly (P<0.01) after treatment and HDL-C was inctrased (P<0.05). NO obvious untoward effect was observed. Conclusion: Pravastatin possesses significant serum lipids-lowening effect and is especially suitable for the treatment of patients with hypercholesterolemia and with elevated LDL-C. |
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| Keywords: | Nephrotic syndrome Hyperlipidemia Pravastatin |
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